I have never made much account of what has proceeded from my own mind; and so long as I gathered no other advantage from the method I employ beyond satisfying myself on some difficulties belonging to the speculative sciences, or endeavoring to regulate my actions according to the principles it taught me, I never thought myself bound to publish anything respecting it. For in what regards manners, everyone is so full of his own wisdom, that there might be found as many reformers as heads, if any were allowed to take upon themselves the task of mending them, except those whom God has constituted the supreme rulers of his people or to whom he has given sufficient grace and zeal to be prophets; and although my speculations greatly pleased myself, I believed that others had theirs, which perhaps pleased them still more. But as soon as I had acquired some general notions respecting physics, and beginning to make trial of them in various particular difficulties, had observed how far they can carry us, and how much they differ from the principles that have been employed up to the present time, I believed that I could not keep them concealed without sinning grievously against the law by which we are bound to promote, as far as in us lies, the general good of mankind.

It is true that the science of medicine, as it now exists, contains few things whose utility is very remarkable: but without any wish to depreciate it, I am confident that there is no one, even among those whose profession it is, who does not admit that all at present known in it is almost nothing in comparison of what remains to be discovered; and that we could free ourselves from an infinity of maladies of body as well as of mind, and perhaps also even from the debility of age, if we had sufficiently ample knowledge of their causes, and of all the remedies provided for us by nature.

But since I designed to employ my whole life in the search after so necessary a science, and since I had fallen in with a path which seems to me such, that if anyone follow it he must inevitably reach the end desired, unless he be hindered either by the shortness of life or the want of experiments, I judged that there could be no more effectual provision against these two impediments than if I were faithfully to communicate to the public all the little I might myself have found, and incite men of superior genius to strive to proceed farther, by contributing, each according to his inclination and ability, to the experiments which it would be necessary to make, and also by informing the public of all they might discover, so that, by the last beginning where those before them had left off, and thus connecting the lives and labours of many, we might collectively proceed much farther than each by himself could do.

This was what I had hoped to make known by the treatise I had written, and so clearly to exhibit the advantage that would thence accrue to the public, as to induce all who have the common good of man at heart, that is, all who are virtuous in truth, and not merely in appearance, or according to opinion, as well to communicate to me the experiments they had already made, as to assist me in those that remain to be made.