My question⁠—that which at the age of fifty brought me to the verge of suicide⁠—was the simplest of questions, lying in the soul of every man from the foolish child to the wisest elder: it was a question without an answer to which one cannot live, as I had found by experience. It was: “What will come of what I am doing today or shall do tomorrow? What will come of my whole life?”

Differently expressed, the question is: “Why should I live, why wish for anything, or do anything?” It can also be expressed thus: “Is there any meaning in my life that the inevitable death awaiting me does not destroy?”

To this one question, variously expressed, I sought an answer in science. And I found that in relation to that question all human knowledge is divided as it were into two opposite hemispheres at the ends of which are two poles: the one a negative and the other a positive; but that neither at the one nor the other pole is there an answer to life’s questions.