But this conclusion in its turn raised a very awkward and difficult question. If a large⁠—a poisonous⁠—dose of the drug had been taken, how, and by whom had that dose been administered? The closest scrutiny of the patient’s arms and legs failed to reveal a single mark such as would be made by a hypodermic needle. This man was clearly no common morphinomaniac; and in the absence of the usual sprinkling of needlemarks, there was nothing to show or suggest whether the drug had been taken voluntarily by the patient himself or administered by someone else.