The case, it is evident, is naturally susceptible of the deductive mode of investigation. The law of an effect of this description is a result of the laws of the separate causes on the combination of which it depends, and is, therefore, in itself capable of being deduced from these laws. This is called the method a priori. The other, or a posteriori method, professes to proceed according to the canons of experimental inquiry. Considering the whole assemblage of concurrent causes which produced the phenomenon, as one single cause, it attempts to ascertain the cause in the ordinary manner, by a comparison of instances. This second method subdivides itself into two different varieties. If it merely collates instances of the effect, it is a method of pure observation. If it operates upon the causes, and tries different combinations of them, in hopes of ultimately hitting the precise combination which will produce the given total effect, it is a method of experiment.
In order more completely to clear up the nature of each of these three methods, and determine which of them deserves the preference, it will be expedient (conformably to a favorite maxim of Lord Chancellor Eldon, to which, though it has often incurred philosophical ridicule, a deeper philosophy will not refuse its sanction) to “clothe them in circumstances.” We shall select for this purpose a case which as yet furnishes no very brilliant example of the success of any of the three methods, but which is all the more suited to illustrate the difficulties inherent in them. Let the subject of inquiry be, the conditions of health and disease in the human body; or (for greater simplicity) the conditions of recovery from a given disease; and in order to narrow the question still more, let it be limited, in the first instance, to this one inquiry: Is, or is not, some particular medicament (mercury, for instance) a remedy for the given disease.
Now, the deductive method would set out from known properties of [pg 321] mercury, and known laws of the human body, and by reasoning from these, would attempt to discover whether mercury will act upon the body when in the morbid condition supposed, in such a manner as would tend to restore health. The experimental method would simply administer mercury in as many cases as possible, noting the age, sex, temperament, and other peculiarities of bodily constitution, the particular form or variety of the disease, the particular stage of its progress, etc., remarking in which of these cases it was attended with a salutary effect, and with what circumstances it was on those occasions combined. The method of simple observation would compare instances of recovery, to find whether they agreed in having been preceded by the administration of mercury; or would compare instances of recovery with instances of failure, to find cases which, agreeing in all other respects, differed only in the fact that mercury had been administered, or that it had not.
§ 7. That the last of these three modes of investigation is applicable to the case, no one has ever seriously contended. No conclusions of value on a subject of such intricacy ever were obtained in that way. The utmost that could result would be a vague general impression for or against the efficacy of mercury, of no avail for guidance unless confirmed by one of the other two methods. Not that the results, which this method strives to obtain, would not be of the utmost possible value if they could be obtained. If all the cases of recovery which presented themselves, in an examination extending to a great number of instances, were cases in which mercury had been administered, we might generalize with confidence from this experience, and should have obtained a conclusion of real value. But no such basis for generalization can we, in a case of this description, hope to obtain. The reason is that which we have spoken of as constituting the characteristic imperfection of the Method of Agreement, Plurality of Causes. Supposing even that mercury does tend to cure the disease, so many other causes, both natural and artificial, also tend to cure it, that there are sure to be abundant instances of recovery in which mercury has not been administered, unless, indeed, the practice be to administer it in all cases; on which supposition it will equally be found in the cases of failure.