The Spaniards found that their cruelty in the first campaign against these untamed savages had inflamed their minds against the viceroyal troops. They attempted, therefore, to use, once more, the language of persuasion, and, offering the insurgents a perfect amnesty for the past, prevailed upon the old inhabitants of the vale of Papigochi to return to their former residences , where, however, they did not long remain faithful to their promised allegiance. The new garrison was established, as had been commanded by the viceroy; but, in 1652, the relentless tribes, again seizing an unguarded moment, burned the barracks, and destroyed in the flames a number of Spaniards, two Franciscan monks, and a Jesuit priest. The soldiery of Barraza and the governor retired from the doomed spot, amid showers of Indian arrows.
In 1653, the war was resumed. The whole country was aroused and armed against these hitherto invincible bands. Other Indian tribes were subdued by the Spanish forces, and their arms were then, once more, turned upon the Tarahumares, at a moment when the Indian chiefs were distant from the field. But the absence of the leaders neither dismayed nor disconcerted these relentless warriors. The Spaniards were again forced to retire; and the viceroy caused an extensive enlistment to be undertaken, and large sums appropriated to crush or pacify the audacious bands. Before the final issue and subjugation, however, the Conde de Alvadeliste, received the king's command to pass from Mexico to the government of Peru, and, awaiting only the arrival of his successor, he sailed from Acapulco for his new viceroyalty.