entire structure or its parts—what are its frailties and what its repairs, without knowing the nature of the materials. And the conception wrought out by Bichat, with his detailed study of the different tissues, acted necessarily on medical questions as the turning of gaslight would act on a dim, oil-lit street, showing new connections and hitherto hidden facts of structure which must be taken into account in considering the symptoms of maladies and the action of medicaments. But results which depend on human conscience and intelligence work slowly, and now at the end of 1829 , most medical practice was still strutting or shambling along the old paths, and there was still scientific work to be done which might have seemed to be a direct sequence of Bichat’s. This great seer did not go beyond the consideration of the tissues as ultimate facts in the living organism, marking the limit of anatomical analysis; but it was open to another mind to say, have not these structures some common basis from which they have all started, as your sarsnet, gauze, net, satin, and velvet from the raw cocoon? Here would be another light, as of oxy-hydrogen, showing the very grain of things, and revising all former explanations. Of this sequence to Bichat’s work, already vibrating along many currents of the European mind, Lydgate was enamoured; he longed to demonstrate the more intimate relations of living structure, and help to define men’s thought more accurately after the true order. The work had not yet been done, but only prepared for those who knew how to use the preparation. What was the primitive tissue? In that way Lydgate put the question—not quite in the way required by the awaiting answer; but such missing of the right word befalls many seekers. And he counted on quiet intervals to be watchfully seized, for taking up the threads of investigation—on many hints to be won from diligent application, not only of the scalpel, but of the microscope, which research had begun to use again with new enthusiasm of reliance. Such was Lydgate’s plan of his future: to do good small work for Middlemarch, and great work for the world.
He was certainly a happy fellow at this time: to be seven-and-twenty, without any fixed vices, with a generous resolution that his action should