What prevented the stomach from digesting itself⁠—as sometimes, in fact, did happen after death? One might answer, life: a special power of resistance of the living protoplasm; but this would be not to recognize the mystical character of such an explanation. The theory of such an everyday phenomenon as fever was full of contradictions. Heightened oxidization resulted in increased warmth, but why was there not an increased expenditure of warmth to correspond? Did the paralysis of the sweat-secretions depend upon contraction of the skin? But such contraction took place only in the case of “chills and fever,” for otherwise, in fever, the skin was more likely to be hot. Prickly heat indicated the central nervous system as the seat of the causes of heightened catabolism as well as the source of that condition of the skin which we were content to call abnormal, because we did not know how to define it.